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Oct 1 2016;142(10):959-965
This is critical
The Pickart 2018 review documented effects on collagen synthesis, anti-inflammatory signaling, nerve regeneration, and stem cell recruitment (Pickart et al., Int J Mol Sci, 2018)
qd, once a day
p=0.003) compared to lidocaine alone
Beyond sleep, DSIP research has revealed potential applications in pain management (showing analgesic effects when administered intracerebroventricularly), addiction treatment (alleviating withdrawal symptoms in 97% of opiate-dependent and 87% of alcohol-dependent patients in one trial), antioxidant defense, and even stroke recovery
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